Racial differences in atrial fibrillation-related bleeding and mortality

Abstract Funding Acknowledgements Type of funding sources: None. Background Adverse outcomes associated with atrial fibrillation (AF) in Asians have not yet been fully elucidated. This study was designed to racial differences the risk for bleeding and effect new-onset AF on mortality. Methods is based a patient-level comparative analysis UK Biobank Korean National Health Insurance Service-Health Screening data. The primary outcome intracranial hemorrhage (ICH). secondary were major gastrointestinal (GI) bleeding. Five-year incidence rates (IR), rate difference (IR those minus IR without AF) ratio divided by calculated. Results Between 2005 2012, we identified 422,121 (mean [SD] age, 55.1 [8.4] years; 54.2% men) 380,763 Whites 57.1 [8.0] 45.1% men). During five-year follow-up period, per 1000 person-years 2.29 (95% CI, 2.22–2.35) 3.55 3.46–3.63) Whites. ICH greater than corresponding White groups. 1.84 1.18–2.51) 0.80 0.56–1.04) For bleeding, only higher Whites, but also 1.3-fold However, different tendencies observed GI Conclusion Despite worse prognosis terms further studies are needed explain trends